Functionally Enhanced siRNA Targeting TNFα Attenuates DSS-induced Colitis and TLR-mediated Immunostimulation in Mice

Tumor necrosis factor (TNFα) is a proinflammatory cytokine involved in the pathogenesis of inflammatory bowel disease (IBD). Although TNFα has been extensively targeted using systemic drugs, the use of antisense and small interfering RNA (siRNA) to drive down its expression at the site of inflammati...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Ocampo, Sandra M, Romero, Carolina, Aviñó, Anna, Burgueño, Joan, Gassull, Miguel A, Bermúdez, Jordi, Eritja, Ramon, Fernandez, Ester, Perales, Jose C
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2012
Soggetti:
Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3277229/
https://ncbi.nlm.nih.gov/pubmed/22044934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.236
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi