Phosphatidylinositol 4-phosphate 5-kinase alpha (PIPKα) regulates neuronal microtubule depolymerase kinesin, KIF2A and suppresses elongation of axon branches

Neuronal morphology is regulated by cytoskeletons. Kinesin superfamily protein 2A (KIF2A) depolymerizes microtubules (MTs) at growth cones and regulates axon pathfinding. The factors controlling KIF2A in neurite development remain totally elusive. Here, using immunoprecipitation with an antibody spe...

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Detalles Bibliográficos
Main Authors: Noda, Yasuko, Niwa, Shinsuke, Homma, Noriko, Fukuda, Hiroyuki, Imajo-Ohmi, Shinobu, Hirokawa, Nobutaka
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2012
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3277188/
https://ncbi.nlm.nih.gov/pubmed/22307638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1107808109
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