Glycogen synthase kinase 3β transfers cytoprotective signaling through connexin 43 onto mitochondrial ATP-sensitive K(+) channels

Despite compelling evidence supporting key roles for glycogen synthase kinase 3β (GSK3β), mitochondrial adenosine triphosphate-sensitive K(+) (mitoK(ATP)) channels, and mitochondrial connexin 43 (Cx43) in cytoprotection, it is not clear how these signaling modules are linked mechanistically. By patc...

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Hlavní autoři: Rottlaender, Dennis, Boengler, Kerstin, Wolny, Martin, Schwaiger, Astrid, Motloch, Lukas J., Ovize, Michel, Schulz, Rainer, Heusch, Gerd, Hoppe, Uta C.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2012
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PNAS Plus
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3277155/
https://ncbi.nlm.nih.gov/pubmed/22238425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1107479109
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