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3β-Methoxy-pregnenolone (MAP4343) as an innovative therapeutic approach for depressive disorders

Emerging evidence suggests that the pathogenesis of depressive disorders (DDs) is associated with neuronal abnormalities in brain microtubule function, including changes in α-tubulin isoforms. Currently available antidepressant drugs may act by rescuing these alterations, but only after long-term tr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bianchi, Massimiliano, Baulieu, Etienne-Emile
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3277154/
https://ncbi.nlm.nih.gov/pubmed/22307636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1121485109
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