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3β-Methoxy-pregnenolone (MAP4343) as an innovative therapeutic approach for depressive disorders

Emerging evidence suggests that the pathogenesis of depressive disorders (DDs) is associated with neuronal abnormalities in brain microtubule function, including changes in α-tubulin isoforms. Currently available antidepressant drugs may act by rescuing these alterations, but only after long-term tr...

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Autori principali: Bianchi, Massimiliano, Baulieu, Etienne-Emile
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3277154/
https://ncbi.nlm.nih.gov/pubmed/22307636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1121485109
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