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3β-Methoxy-pregnenolone (MAP4343) as an innovative therapeutic approach for depressive disorders

Emerging evidence suggests that the pathogenesis of depressive disorders (DDs) is associated with neuronal abnormalities in brain microtubule function, including changes in α-tubulin isoforms. Currently available antidepressant drugs may act by rescuing these alterations, but only after long-term tr...

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Detalhes bibliográficos
Main Authors: Bianchi, Massimiliano, Baulieu, Etienne-Emile
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3277154/
https://ncbi.nlm.nih.gov/pubmed/22307636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1121485109
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