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Convergent structural alterations define SWItch/Sucrose NonFermentable (SWI/SNF) chromatin remodeler as a central tumor suppressive complex in pancreatic cancer

Defining the molecular genetic alterations underlying pancreatic cancer may provide unique therapeutic insight for this deadly disease. Toward this goal, we report here an integrative DNA microarray and sequencing-based analysis of pancreatic cancer genomes. Notable among the alterations newly ident...

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Hlavní autoři: Shain, A. Hunter, Giacomini, Craig P., Matsukuma, Karen, Karikari, Collins A., Bashyam, Murali D., Hidalgo, Manuel, Maitra, Anirban, Pollack, Jonathan R.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3277150/
https://ncbi.nlm.nih.gov/pubmed/22233809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1114817109
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