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Complementary costimulation of human T-cell subpopulations by cluster of differentiation 28 (CD28) and CD81

Cluster of differentiation 81 (CD81) is a widely expressed tetraspanin molecule that physically associates with CD4 and CD8 on the surface of human T cells. Coengagement of CD81 and CD3 results in the activation and proliferation of T cells. CD81 also costimulated mouse T cells that lack CD28, sugge...

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Detalhes bibliográficos
Main Authors: Sagi, Yael, Landrigan, Angela, Levy, Ronald, Levy, Shoshana
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3277132/
https://ncbi.nlm.nih.gov/pubmed/22307619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1121307109
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