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A six-nucleotide deletion polymorphism in the casp8 promoter is associated with reduced risk of esophageal and gastric cancers in Kashmir valley

BACKGROUND: Caspase-8 (CASP8) is a key regulator of apoptosis or programmed cell death, an essential defense mechanism against hyperproliferation and malignancy. To evaluate the role of CASP8 polymorphisms in esophageal (EC) and gastric cancers (GC) in the Kashmir valley, we examined the risk due to...

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Autors principals: Malik, Manzoor Ahmad, Zargar, Showkat Ali, Mittal, Balraj
Format: Artigo
Idioma:Inglês
Publicat: Medknow Publications & Media Pvt Ltd 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3276982/
https://ncbi.nlm.nih.gov/pubmed/22345985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0971-6866.92090
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