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A six-nucleotide deletion polymorphism in the casp8 promoter is associated with reduced risk of esophageal and gastric cancers in Kashmir valley

BACKGROUND: Caspase-8 (CASP8) is a key regulator of apoptosis or programmed cell death, an essential defense mechanism against hyperproliferation and malignancy. To evaluate the role of CASP8 polymorphisms in esophageal (EC) and gastric cancers (GC) in the Kashmir valley, we examined the risk due to...

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Bibliographische Detailangaben
Hauptverfasser: Malik, Manzoor Ahmad, Zargar, Showkat Ali, Mittal, Balraj
Format: Artigo
Sprache:Inglês
Veröffentlicht: Medknow Publications & Media Pvt Ltd 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3276982/
https://ncbi.nlm.nih.gov/pubmed/22345985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0971-6866.92090
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