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A six-nucleotide deletion polymorphism in the casp8 promoter is associated with reduced risk of esophageal and gastric cancers in Kashmir valley

BACKGROUND: Caspase-8 (CASP8) is a key regulator of apoptosis or programmed cell death, an essential defense mechanism against hyperproliferation and malignancy. To evaluate the role of CASP8 polymorphisms in esophageal (EC) and gastric cancers (GC) in the Kashmir valley, we examined the risk due to...

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Detalhes bibliográficos
Main Authors: Malik, Manzoor Ahmad, Zargar, Showkat Ali, Mittal, Balraj
Formato: Artigo
Idioma:Inglês
Publicado em: Medknow Publications & Media Pvt Ltd 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3276982/
https://ncbi.nlm.nih.gov/pubmed/22345985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0971-6866.92090
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