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LRRK2 in Transcription and Translation Regulation: Relevance for Parkinson’s Disease

Parkinson’s disease (PD) is the most common neurodegenerative movement disorder and is characterized by the selective loss of dopaminergic neurons and the presence of Lewy bodies. Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene are the most frequent cause of both familial and sporadic PD....

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Bibliographic Details
Main Authors: Dorval, Véronique, Hébert, Sébastien S.
Format: Artigo
Language:Inglês
Published: Frontiers Research Foundation 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3276974/
https://ncbi.nlm.nih.gov/pubmed/22363314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2012.00012
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