MYC Gene Amplification is Often Acquired in Lethal Distant Breast Cancer Metastases of Unamplified Primary Tumors

In breast cancer, amplification of MYC is consistently observed in aggressive forms of disease and correlates with poor prognosis and distant metastases. However, to date, a systematic analysis of MYC amplification in metastatic breast cancers has not been reported. Specifically, whether the MYC amp...

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Autors principals: Singhi, Aatur D., Cimino-Mathews, Ashley, Jenkins, Robert B., Lan, Fusheng, Fink, Stephanie R., Nassar, Hind, Vang, Russell, Fetting, John, Hicks, Jessica, Sukumar, Saraswati, De Marzo, Angelo M., Argani, Pedram
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3276715/
https://ncbi.nlm.nih.gov/pubmed/22056952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/modpathol.2011.171
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