ELOVL4 protein preferentially elongates 20:5n3 to very long chain PUFAs over 20:4n6 and 22:6n3

We hypothesized that reduction/loss of very long chain PUFAs (VLC-PUFAs) due to mutations in the ELOngase of very long chain fatty acid-4 (ELOVL4) protein contributes to retinal degeneration in autosomal dominant Stargardt-like macular dystrophy (STGD3) and age-related macular degeneration; hence, i...

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Autors principals: Yu, Man, Benham, Aaron, Logan, Sreemathi, Brush, R. Steven, Mandal, Md Nawajes A., Anderson, Robert E., Agbaga, Martin-Paul
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Biochemistry and Molecular Biology 2012
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Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3276472/
https://ncbi.nlm.nih.gov/pubmed/22158834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M021386
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