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Protein kinase Cβ deficiency attenuates obesity syndrome of ob/ob mice by promoting white adipose tissue remodeling

To explore the role of leptin in PKCβ action and to determine the protective potential of PKCβ deficiency on profound obesity, double knockout (DBKO) mice lacking PKCβ and ob genes were created, and key parameters of metabolism and body composition were studied. DBKO mice had similar caloric intake...

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Détails bibliographiques
Auteurs principaux: Huang, Wei, Bansode, Rishipal R., Bal, Naresh C., Mehta, Madhu, Mehta, Kamal D.
Format: Artigo
Langue:Inglês
Publié: The American Society for Biochemistry and Molecular Biology 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3276460/
https://ncbi.nlm.nih.gov/pubmed/22210924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M019687
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