Fibroid explants reveal a higher sensitivity against MDM2-inhibitor nutlin-3 than matching myometrium

BACKGROUND: Spontaneous cessation of growth is a frequent finding in uterine fibroids. Increasing evidence suggests an important role of cellular senescence in this growth control. Deciphering the underlying mechanisms of growth control that can be expected not only to shed light on the biology of t...

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Detalhes bibliográficos
Main Authors: Markowski, Dominique N, Helmke, Burkhard M, Radtke, Arlo, Froeb, Jennifer, Belge, Gazanfer, Bartnitzke, Sabine, Wosniok, Werner, Czybulka-Jachertz, Iris, Deichert, Ulrich, Bullerdiek, Jörn
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3276409/
https://ncbi.nlm.nih.gov/pubmed/22233735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6874-12-2
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