Fibroid explants reveal a higher sensitivity against MDM2-inhibitor nutlin-3 than matching myometrium

BACKGROUND: Spontaneous cessation of growth is a frequent finding in uterine fibroids. Increasing evidence suggests an important role of cellular senescence in this growth control. Deciphering the underlying mechanisms of growth control that can be expected not only to shed light on the biology of t...

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Autori principali: Markowski, Dominique N, Helmke, Burkhard M, Radtke, Arlo, Froeb, Jennifer, Belge, Gazanfer, Bartnitzke, Sabine, Wosniok, Werner, Czybulka-Jachertz, Iris, Deichert, Ulrich, Bullerdiek, Jörn
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3276409/
https://ncbi.nlm.nih.gov/pubmed/22233735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6874-12-2
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