Partial versus Productive Immunoglobulin Heavy Locus Rearrangements in Chronic Lymphocytic Leukemia: Implications for B-Cell Receptor Stereotypy

The frequent occurrence of stereotyped heavy complementarity-determining region 3 (VH CDR3) sequences among unrelated cases with chronic lymphocytic leukemia (CLL) is widely taken as evidence for antigen selection. Stereotyped VH CDR3 sequences are often defined by the selective association of certa...

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Main Authors: Tsakou, Eugenia, Agathagelidis, Andreas, Boudjoghra, Myriam, Raff, Thorsten, Dagklis, Antonis, Chatzouli, Maria, Smilevska, Tatjana, Bourikas, George, Merle-Beral, Helene, Manioudaki-Kavallieratou, Eleni, Anagnostopoulos, Achilles, Brüggemann, Monika, Davi, Frederic, Stamatopoulos, Kostas, Belessi, Chrysoula
Format: Artigo
Sprog:Inglês
Udgivet: ScholarOne 2011
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3276399/
https://ncbi.nlm.nih.gov/pubmed/21968789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2011.00216
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