Toll-like receptor signaling pathway in chronic lymphocytic leukemia: distinct gene expression profiles of potential pathogenic significance in specific subsets of patients

BACKGROUND: Signaling through the B-cell receptor appears to be a major contributor to the pathogenesis of chronic lymphocytic leukemia. Toll-like receptors bridge the innate and adaptive immune responses by acting as co-stimulatory signals for B cells. The available data on the expression of Toll-l...

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Main Authors: Arvaniti, Eleni, Ntoufa, Stavroula, Papakonstantinou, Nikos, Touloumenidou, Tasoula, Laoutaris, Nikolaos, Anagnostopoulos, Achilles, Lamnissou, Klea, Caligaris-Cappio, Federico, Stamatopoulos, Kostas, Ghia, Paolo, Muzio, Marta, Belessi, Chrysoula
Format: Artigo
Jezik:Inglês
Izdano: Ferrata Storti Foundation 2011
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3208682/
https://ncbi.nlm.nih.gov/pubmed/21750087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2011.044792
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