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Significance analysis and statistical dissection of variably methylated regions
It has recently been proposed that variation in DNA methylation at specific genomic locations may play an important role in the development of complex diseases such as cancer. Here, we develop 1- and 2-group multiple testing procedures for identifying and quantifying regions of DNA methylation varia...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3276267/ https://ncbi.nlm.nih.gov/pubmed/21685414 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biostatistics/kxr013 |
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