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The C57BL/6J Mouse Strain Background Modifies the Effect of a Mutation in Bcl2l2
Bcl2l2 encodes BCL-W, an antiapoptotic member of the BCL-2 family of proteins. Intercross of Bcl2l2 +/− mice on a mixed C57BL/6J, 129S5 background produces Bcl2l2 −/− animals with the expected frequency. In contrast, intercross of Bcl2l2 +/− mice on a congenic C57BL/6J background produces relatively...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Genetics Society of America
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3276190/ https://ncbi.nlm.nih.gov/pubmed/22384386 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.111.000778 |
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