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Diet induced obesity in two C57BL/6 substrains with intact or mutant Nicotinamide Nucleotide Transhydrogenase (Nnt) gene
The C57BL/6J (B6/J) male mouse represents a standard for diet induced obesity (DIO) and is unique in expressing a loss-of-function Nicotinamide Nucleotide Transhydrogenase (Nnt) gene. This mutation was associated with a marked reduction in glucose-stimulated insulin secretion from B6/J islets in vit...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2888716/ https://ncbi.nlm.nih.gov/pubmed/20057372 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oby.2009.477 |
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