Diet induced obesity in two C57BL/6 substrains with intact or mutant Nicotinamide Nucleotide Transhydrogenase (Nnt) gene

The C57BL/6J (B6/J) male mouse represents a standard for diet induced obesity (DIO) and is unique in expressing a loss-of-function Nicotinamide Nucleotide Transhydrogenase (Nnt) gene. This mutation was associated with a marked reduction in glucose-stimulated insulin secretion from B6/J islets in vit...

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Main Authors: Nicholson, Anthony, Reifsnyder, Peter C., Malcolm, Rachel, Lucas, Charlotte A., MacGregor, Grant R., Zhang, Weidong, Leiter, Edward H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2888716/
https://ncbi.nlm.nih.gov/pubmed/20057372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oby.2009.477
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