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Genome-Wide Analysis to Identify Pathways Affecting Telomere-Initiated Senescence in Budding Yeast

In telomerase-deficient yeast cells, like equivalent mammalian cells, telomeres shorten over many generations until a period of senescence/crisis is reached. After this, a small fraction of cells can escape senescence, principally using recombination-dependent mechanisms. To investigate the pathways...

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Detalhes bibliográficos
Main Authors: Chang, Hsin-Yu, Lawless, Conor, Addinall, Stephen G., Oexle, Sarah, Taschuk, Morgan, Wipat, Anil, Wilkinson, Darren J., Lydall, David
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3276134/
https://ncbi.nlm.nih.gov/pubmed/22384331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.111.000216
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