17α-Ethynyl-5α-androstane-3α, 17β-diol Treatment of MNU-Induced Mammary Cancer in Rats

N-methyl-N-nitrosourea (MNU) induces estrogen-dependent mammary tumors in female Lewis rats. We explored the antineoplastic activity of a synthetic androstane derivative, 17α-ethynyl-5α-androstane-3α, 17β-diol (HE3235), as a single agent or in combination with docetaxel compared to tamoxifen, anastr...

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Main Authors: Ahlem, Clarence N., Frincke, James M., White, Steven K., Reading, Christopher L., Trauger, Richard J., Lakshmanaswamy, Rajkumar
格式: Artigo
語言:Inglês
出版: SAGE-Hindawi Access to Research 2011
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Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3276108/
https://ncbi.nlm.nih.gov/pubmed/22332014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2011/618757
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