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A small segment of polyoma virus DNA enhances the expression of a cloned beta-globin gene over a distance of 1400 base pairs.

The hemoglobin beta-1 gene of the rabbit was linked to a 244 bp DNA fragment from the beginning of the polyoma virus late region, not including the viral origin of replication. After transfection of such recombinant DNAs into mouse 3T6 and human HeLa cells, the polyoma sequences were found to strong...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Principais autores: de Villiers, J, Schaffner, W
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 1981
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC327601/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6275354/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/9.23.6251
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