MRP8/ABCC11 Expression Is Regulated by Dexamethasone in Breast Cancer Cells and Is Associated to Progesterone Receptor Status in Breast Tumors

The ATP-binding cassette multidrug resistance protein 8 (MRP8/ABCC11) mediates the excretion of anticancer drugs. ABCC11 mRNA and protein levels were enhanced by DEX (dexamethasone) and by PROG (progesterone) in MCF7 (progesterone receptor-(PR-) positive) but not in MDA-MB-231 (PR-negative) breast c...

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Detalhes bibliográficos
Main Authors: Honorat, Mylène, Mesnier, Aurélia, Vendrell, Julie, Di Pietro, Attilio, Lin, Valérie, Dumontet, Charles, Cohen, Pascale, Payen, Léa
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE-Hindawi Access to Research 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3275985/
https://ncbi.nlm.nih.gov/pubmed/22332017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2011/807380
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