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Antiviral activities of hybrids of two major human leukocyte interferons.

Four hybrid human leukocyte interferon (LeIF or IFN-alpha) genes have been constructed by in vitro recombination of LeIF-A (IFN-alpha 2) and LeIF-D (IFN-alpha 1) genes at common restriction endonuclease sites located within their coding regions. These hybrid genes have been expressed in E. coli unde...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Principais autores: Weck, P K, Apperson, S, Stebbing, N, Gray, P W, Leung, D, Shepard, H M, Goeddel, D V
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 1981
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC327591/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6171779/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/9.22.6153
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