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Antiviral activities of hybrids of two major human leukocyte interferons.

Four hybrid human leukocyte interferon (LeIF or IFN-alpha) genes have been constructed by in vitro recombination of LeIF-A (IFN-alpha 2) and LeIF-D (IFN-alpha 1) genes at common restriction endonuclease sites located within their coding regions. These hybrid genes have been expressed in E. coli unde...

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Bibliographic Details
Main Authors: Weck, P K, Apperson, S, Stebbing, N, Gray, P W, Leung, D, Shepard, H M, Goeddel, D V
Format: Artigo
Language:Inglês
Published: 1981
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC327591/
https://ncbi.nlm.nih.gov/pubmed/6171779
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