Synthesis of 4-triazolopyrimidinone nucleotide and its application in synthesis of 5-methylcytosine-containing oligodeoxyribonucleotides.

5'-0-Dimethoxytritylthymidine (2) was phosphorylated and base-modified simultaneously to yield the 4-triazolopyrimidinone nucleotide (3). Coupling between (3) and other common deoxyribonucleotides gave a fully protected nonamer (4). Deblocking under different conditions yielded the nonamer as phosph...

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Bibliografski detalji

Izdano u:	Nucleic Acids Res
Glavni autor:	Sung, W L
Format:	Artigo
Jezik:	Inglês
Izdano:	Oxford University Press 1981
Teme:	Research Article
Online pristup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC327590/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7312633/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/9.22.6139
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