Synthesis of 4-triazolopyrimidinone nucleotide and its application in synthesis of 5-methylcytosine-containing oligodeoxyribonucleotides.
5'-0-Dimethoxytritylthymidine (2) was phosphorylated and base-modified simultaneously to yield the 4-triazolopyrimidinone nucleotide (3). Coupling between (3) and other common deoxyribonucleotides gave a fully protected nonamer (4). Deblocking under different conditions yielded the nonamer as phosph...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Nucleic Acids Res |
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| Prif Awdur: | |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
Oxford University Press
1981
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC327590/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7312633/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/9.22.6139 |
| Tagiau: |
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