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Monoclonal Antibody That Blocks the Toll-Like Receptor 5 Binding Region of Flagellin
The conserved domain of bacteria-derived flagellin coupling Toll-like receptor 5 (TLR5) activates NF-κB and MAPK signaling transductions, which subsequently regulate the transcription and expression of genes encoding immune mediators. However, whether the flagellin binding monoclonal antibody (MAb)...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Mary Ann Liebert, Inc.
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3275795/ https://ncbi.nlm.nih.gov/pubmed/22316487 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hyb.2011.0083 |
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