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Electroporation mediated in-vivo Gene Delivery of the Na(+)/K(+)-ATPase pump Reduced Lung Injury in a mouse model of Lung Contusion

OBJECTIVE: Lung contusion (LC) is an independent risk factor for Adult Respiratory Distress Syndrome (ARDS). The final common pathway in ARDS involves accumulation of fluid in the alveoli. In this study we demonstrate the application of a potential gene therapy approach by delivering the Na(+)/K(+)-...

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Detalhes bibliográficos
Main Authors: Machado-Aranda, David A, Madathilparambil, Suresh, Yu, Bi, Raghavendran, Krishnan
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3275777/
https://ncbi.nlm.nih.gov/pubmed/22310113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TA.0b013e31823f0606
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