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Increased phospholipase A(2) and lyso-phosphatidylcholine levels are associated with surfactant dysfunction in lung contusion injury in mice

OBJECTIVE: Surfactant dysfunction is an important pathological disturbance in various forms of acute inflammatory lung injury. Previously we reported the presence of significant alterations in the composition and activity of pulmonary surfactant in blunt trauma-induced bilateral lung contusion (LC)...

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Autores principales: Machado-Aranda, David, Wang, Zhengdong, Yu, Bi, Suresh, M V, Notter, Robert H., Raghavendran, Krishnan
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3509248/
https://ncbi.nlm.nih.gov/pubmed/22853859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2012.05.043
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