Structural and Functional Insights into Endoglin Ligand Recognition and Binding

Endoglin, a type I membrane glycoprotein expressed as a disulfide-linked homodimer on human vascular endothelial cells, is a component of the transforming growth factor (TGF)-β receptor complex and is implicated in a dominant vascular dysplasia known as hereditary hemorrhagic telangiectasia as well...

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Autors principals: Alt, Aaron, Miguel-Romero, Laura, Donderis, Jordi, Aristorena, Mikel, Blanco, Francisco J., Round, Adam, Rubio, Vicente, Bernabeu, Carmelo, Marina, Alberto
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3275592/
https://ncbi.nlm.nih.gov/pubmed/22347366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029948
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