The Role of the TGF-β Coreceptor Endoglin in Cancer

Endoglin (CD105) is an auxiliary membrane receptor of transforming growth factor beta (TGF-β) that interacts with type I and type II TGF-β receptors and modulates TGF-β signaling. Endoglin is overexpressed in the tumor-associated vascular endothelium, where it modulates angiogenesis. This feature ma...

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Bibliografiske detaljer
Udgivet i:ScientificWorldJournal
Main Authors: Pérez-Gómez, Eduardo, del Castillo, Gaelle, Santibáñez, Juan Francisco, Lêpez-Novoa, Jose Miguel, Bernabéu, Carmelo, Quintanilla, Miguel
Format: Artigo
Sprog:Inglês
Udgivet: TheScientificWorldJOURNAL 2010
Fag:
Review Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5763795/
https://ncbi.nlm.nih.gov/pubmed/21170488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1100/tsw.2010.230
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