Characterization of Ku702–NLS as Bipartite Nuclear Localization Sequence for Non-Viral Gene Delivery

Several barriers have to be overcome in order to achieve gene expression in target cells, e.g. cellular uptake, endosomal release and translocation to the nucleus. Nuclear localization sequences (NLS) enhance gene delivery by increasing the uptake of plasmid DNA (pDNA) to the nucleus. So far, only m...

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Detaylı Bibliyografya
Asıl Yazarlar: Matschke, Johannes, Bohla, Alexander, Maucksch, Christof, Mittal, Rashmi, Rudolph, Carsten, Rosenecker, Joseph
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2012
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3275586/
https://ncbi.nlm.nih.gov/pubmed/22347357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024615
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