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Long-Term Gene Therapy Causes Transgene-Specific Changes in the Morphology of Regenerating Retinal Ganglion Cells

Recombinant adeno-associated viral (rAAV) vectors can be used to introduce neurotrophic genes into injured CNS neurons, promoting survival and axonal regeneration. Gene therapy holds much promise for the treatment of neurotrauma and neurodegenerative diseases; however, neurotrophic factors are known...

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Detalhes bibliográficos
Main Authors: Rodger, Jennifer, Drummond, Eleanor S., Hellström, Mats, Robertson, Donald, Harvey, Alan R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3275572/
https://ncbi.nlm.nih.gov/pubmed/22347429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031061
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