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Long-Term Gene Therapy Causes Transgene-Specific Changes in the Morphology of Regenerating Retinal Ganglion Cells

Recombinant adeno-associated viral (rAAV) vectors can be used to introduce neurotrophic genes into injured CNS neurons, promoting survival and axonal regeneration. Gene therapy holds much promise for the treatment of neurotrauma and neurodegenerative diseases; however, neurotrophic factors are known...

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Autori principali: Rodger, Jennifer, Drummond, Eleanor S., Hellström, Mats, Robertson, Donald, Harvey, Alan R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3275572/
https://ncbi.nlm.nih.gov/pubmed/22347429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031061
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