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HER2 and TOP2A in high-risk early breast cancer patients treated with adjuvant epirubicin-based dose-dense sequential chemotherapy

BACKGROUND: HER2 and TOP2A parameters (gene status, mRNA and protein expression) have individually been associated with the outcome of patients treated with anthracyclines. The aim of this study was to comprehensively evaluate the prognostic/predictive significance of the above parameters in early,...

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Hauptverfasser: Fountzilas, George, Valavanis, Christos, Kotoula, Vassiliki, Eleftheraki, Anastasia G, Kalogeras, Konstantine T, Tzaida, Olympia, Batistatou, Anna, Kronenwett, Ralf, Wirtz, Ralph M, Bobos, Mattheos, Timotheadou, Eleni, Soupos, Nikolaos, Pentheroudakis, George, Gogas, Helen, Vlachodimitropoulos, Dimitrios, Polychronidou, Genovefa, Aravantinos, Gerasimos, Koutras, Angelos, Christodoulou, Christos, Pectasides, Dimitrios, Arapantoni, Petroula
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2012
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3275536/
https://ncbi.nlm.nih.gov/pubmed/22240029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-10-10
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