Deletion of CaMKK2 from the Liver Lowers Blood Glucose and Improves Whole-Body Glucose Tolerance in the Mouse

Ca(2+)/calmodulin-dependent protein kinase kinase 2 (CaMKK2) is a member of the Ca(2+)/CaM-dependent protein kinase family that is expressed abundantly in brain. Previous work has revealed that CaMKK2 knockout (CaMKK2 KO) mice eat less due to a central nervous system -signaling defect and are protec...

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Autores principales: Anderson, Kristin A., Lin, Fumin, Ribar, Thomas J., Stevens, Robert D., Muehlbauer, Michael J., Newgard, Christopher B., Means, Anthony R.
Formato: Artigo
Lenguaje:Inglês
Publicado: Endocrine Society 2012
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Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3275166/
https://ncbi.nlm.nih.gov/pubmed/22240810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2011-1299
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