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Gene Expression Profile Normalization in Cloned Mice by Trichostatin A Treatment

Cloning mammals by somatic cell nuclear transfer (SCNT) has become an established procedure, but the success rate remains low and gene expression abnormalities are also observed. In addition, SCNT pups exhibited an abnormal gene expression profile with a high degree of heterogeneity among individual...

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Autori principali: Kohda, Takashi, Kishigami, Satoshi, Kaneko-Ishino, Tomoko, Wakayama, Teruhiko, Ishino, Fumitoshi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc. 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3275098/
https://ncbi.nlm.nih.gov/pubmed/22257163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cell.2011.0062
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