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High yielding allylation of a chiral secondary alcohol containing base sensitive functional groups
Inhibitors of neuronal nitric oxide synthase, based on a chiral pyrrolidine scaffold, show promise for the treatment of certain neurodegenerative diseases. We recently reported the synthesis of a series of selective inhibitors, but the method was limited at a key step of formingan allyl ether interm...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3274772/ https://ncbi.nlm.nih.gov/pubmed/22328795 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2011.12.120 |
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