Temporal course of cerebrospinal fluid dynamics and amyloid accumulation in the aging rat brain from three to thirty months

BACKGROUND: Amyloid accumulation in the brain parenchyma is a hallmark of Alzheimer's disease (AD) and is seen in normal aging. Alterations in cerebrospinal fluid (CSF) dynamics are also associated with normal aging and AD. This study analyzed CSF volume, production and turnover rate in relatio...

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Detaylı Bibliyografya
Asıl Yazarlar: Chiu, Catherine, Miller, Miles C, Caralopoulos, Ilias N, Worden, Michael S, Brinker, Thomas, Gordon, Zachary N, Johanson, Conrad E, Silverberg, Gerald D
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2012
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3274479/
https://ncbi.nlm.nih.gov/pubmed/22269091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-8118-9-3
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