Temporal course of cerebrospinal fluid dynamics and amyloid accumulation in the aging rat brain from three to thirty months

BACKGROUND: Amyloid accumulation in the brain parenchyma is a hallmark of Alzheimer's disease (AD) and is seen in normal aging. Alterations in cerebrospinal fluid (CSF) dynamics are also associated with normal aging and AD. This study analyzed CSF volume, production and turnover rate in relatio...

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Hlavní autoři: Chiu, Catherine, Miller, Miles C, Caralopoulos, Ilias N, Worden, Michael S, Brinker, Thomas, Gordon, Zachary N, Johanson, Conrad E, Silverberg, Gerald D
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2012
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3274479/
https://ncbi.nlm.nih.gov/pubmed/22269091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-8118-9-3
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