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Intrastriatal convection-enhanced delivery results in widespread perivascular distribution in a pre-clinical model
BACKGROUND: Convection-enhanced delivery (CED), a direct method for drug delivery to the brain through intraparenchymal microcatheters, is a promising strategy for intracerebral pharmacological therapy. By establishing a pressure gradient at the tip of the catheter, drugs can be delivered in uniform...
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| Main Authors: | , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
BioMed Central
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3274474/ https://ncbi.nlm.nih.gov/pubmed/22264361 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-8118-9-2 |
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