R-848 triggers the expression of TLR7/8 and suppresses HIV replication in monocytes

BACKGROUND: Toll-like receptors (TLR) 7 and 8 are important in single-stranded viral RNA recognition and may play a role in HIV infection and disease progression. We analyzed TLR7/8 expression and signaling in monocytes from HIV-infected and uninfected subjects to investigate a pathway with new pote...

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Main Authors: Nian, Hua, Geng, Wen-Qing, Cui, Hua-Lu, Bao, Ming-jia, Zhang, Zi-ning, Zhang, Min, Pan, Ying, Hu, Qing-Hai, Shang, Hong
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2012
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3274444/
https://ncbi.nlm.nih.gov/pubmed/22243920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2334-12-5
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