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R-848 triggers the expression of TLR7/8 and suppresses HIV replication in monocytes
BACKGROUND: Toll-like receptors (TLR) 7 and 8 are important in single-stranded viral RNA recognition and may play a role in HIV infection and disease progression. We analyzed TLR7/8 expression and signaling in monocytes from HIV-infected and uninfected subjects to investigate a pathway with new pote...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BioMed Central
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3274444/ https://ncbi.nlm.nih.gov/pubmed/22243920 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2334-12-5 |
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