Protective Antigen Antibody Augments Hemodynamic Support in Anthrax Lethal Toxin Shock in Canines

Background. Anthrax-associated shock is closely linked to lethal toxin (LT) release and is highly lethal despite conventional hemodynamic support. We investigated whether protective antigen–directed monoclonal antibody (PA-mAb) treatment further augments titrated hemodynamic support. Methods and Res...

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Autors principals: Barochia, Amisha V., Cui, Xizhong, Sun, Junfeng, Li, Yan, Solomon, Steven B., Migone, Thi-Sau, Subramanian, G. Mani, Bolmer, Sally D., Eichacker, Peter Q.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2012
Matèries:
Major Articles and Brief Reports
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3274375/
https://ncbi.nlm.nih.gov/pubmed/22223857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jir834
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