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Anthrax Lethal and Edema Toxins Produce Different Patterns of Cardiovascular and Renal Dysfunction and Synergistically Decrease Survival in Canines

Background. High mortality in the 2001 US and recent European anthrax outbreaks suggests that better understanding of the effects of the toxins produced by this bacterium is needed to improve treatment. Methods and results. Here, 24-h edema (ETx) and lethal (LeTx) toxin infusions were investigated f...

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Bibliografiske detaljer
Main Authors: Sweeney, Daniel A., Cui, Xizhong, Solomon, Steven B., Vitberg, David A., Migone, Thi S., Scher, Dara, Danner, Robert L., Natanson, Charles, Subramanian, G. Mani, Eichacker, Peter Q.
Format: Artigo
Sprog:Inglês
Udgivet: The University of Chicago Press 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3061475/
https://ncbi.nlm.nih.gov/pubmed/21067373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/657408
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