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Optical Trapping with High Forces Reveals Unexpected Behaviors of Prion Fibrils

Amyloid fibrils are important in diverse cellular functions, feature in many human diseases and have potential applications in nanotechnology. Here we developed methods that combine optical trapping and fluorescent imaging to characterize the forces that govern the integrity of amyloid fibrils forme...

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Autori principali: Dong, Jijun, Castro, Carlos E., Boyce, Mary C., Lang, Matthew J., Lindquist, Susan
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3274366/
https://ncbi.nlm.nih.gov/pubmed/21113168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1954
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