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Extracellular leucine-rich repeat proteins are required to organize the apical extracellular matrix and maintain epithelial junction integrity in C. elegans

Epithelial cells are linked by apicolateral junctions that are essential for tissue integrity. Epithelial cells also secrete a specialized apical extracellular matrix (ECM) that serves as a protective barrier. Some components of the apical ECM, such as mucins, can influence epithelial junction remod...

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Autori principali: Mancuso, Vincent P., Parry, Jean M., Storer, Luke, Poggioli, Corey, Nguyen, Ken C. Q., Hall, David H., Sundaram, Meera V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Company of Biologists 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3274359/
https://ncbi.nlm.nih.gov/pubmed/22278925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.075135
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