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Extracellular leucine-rich repeat proteins are required to organize the apical extracellular matrix and maintain epithelial junction integrity in C. elegans

Epithelial cells are linked by apicolateral junctions that are essential for tissue integrity. Epithelial cells also secrete a specialized apical extracellular matrix (ECM) that serves as a protective barrier. Some components of the apical ECM, such as mucins, can influence epithelial junction remod...

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Bibliographic Details
Main Authors: Mancuso, Vincent P., Parry, Jean M., Storer, Luke, Poggioli, Corey, Nguyen, Ken C. Q., Hall, David H., Sundaram, Meera V.
Format: Artigo
Language:Inglês
Published: Company of Biologists 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3274359/
https://ncbi.nlm.nih.gov/pubmed/22278925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.075135
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