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Hepatocellular carcinoma in a gene therapy research subject with ornithine transcarbamylase deficiency

A 66 year old woman who is a manifesting heterozygote for ornithine transcarbamylase deficiency (OTCD) presented with hepatocellular carcinoma (HCC). Fourteen years prior to this presentation she participated in a phase I gene therapy study which used an adenoviral vector, thought to be non-oncogeni...

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Bibliografiske detaljer
Main Authors: Wilson, James M., Shchelochkov, Oleg A., Gallagher, Renata C., Batshaw, Mark L.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3273986/
https://ncbi.nlm.nih.gov/pubmed/22129577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgme.2011.10.016
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