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Robust nuclear lamina-based cell classification of aging and senescent cells

Changes in the shape of the nuclear lamina are exhibited in senescent cells, as well as in cells expressing mutations in lamina genes. To identify cells with defects in the nuclear lamina we developed an imaging method that quantifies the intensity and curvature of the nuclear lamina. We show that t...

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Detaylı Bibliyografya
Asıl Yazarlar: Righolt, Christiaan H., van 't Hoff, Merel L.R., Vermolen, Bart J., Young, Ian T., Raz, Vered
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Impact Journals LLC 2011
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3273899/
https://ncbi.nlm.nih.gov/pubmed/22199022
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